The Bottom Line

Between its comprehensive, doctor-made formula and outstanding customer satisfaction, Alpha Vita’s Arthrogenix® is a standout #1.

This product contains UC-II Undenatured Collagen, 5-Loxin® Advanced Boswellia, 99% Turmeric Curucminoids, Ginger Root, Natural Eggshell Membrane, Lobelia, KSM®66 Ashwaganda Root, and California poppy—all of which are extremely powerful and rare joint health powerhouses.

Intelligent Reviews was able to locate an impressive 2022 survey on this product:

• 91% customer satisfaction**
• 93% who switched to Arthrogenix® said it was best joint health supplement they've ever tried **
• Over 82% reported improvements in muscle tightness, cramps, and joint flexibility**

Arthrogenix gets to the core of your joint discomfort and help support your body’s natural inflammatory response, to help reduce pain. Clinical studies prove it reduces pain and stiffness and improves flexibility in just 7 to 10 days.

In fact, this is proven by clinical research published in The International Journal of Medical Sciences. Reduction in WOMAC scores measuring pain, stiffness and physical function limits plunged from baseline 80.6 to 33.2 after taking ingredients exclusive to Arthrogenix®.

The key to this superior product is their wildcrafted extraction process, improving oral absorption rates 29 times greater than unformulated non-wildcrafted products. Backed by extensive research and high-quality ingredients, Arthrogenix stands out, offering superior value and quality at a reasonable price point.

Finally, Alpha Vita Labs™ backs up every purchase with an impressive 120- day money-back guarantee. We can confidently call Arthrogenix® our #1 joint health supplement of 2022.

The Bottom Line

Instaflex was our second choice because of its well-sourced and complementary ingredients.It contains a clinically recommended amount of Boswellia, and UC-II Collagen the two most clinically proven ingredients on the market.

These ingredients work well together in strengthening and maintaining bone health through the stimulation of proteins and the absorption of calcium.

In short, our experts have chosen Instaflex as the #2 in the list because of its remarkable effectiveness and optimal dosage. It also has a neutral taste and a reasonable price. Moreover, the amount of Hylaronic is minimal and can't be considered.

To top things off, Instaflex backs all of their products with comprehensive, 90-day return policy, zero questions asked.

Natural, safe GRAS ingredient. Non-chemical, eco-friendly manufacturing process in an FDA regulated GMP facility. Made in the USA. 100% domestic. Contains no fillers, binders, or synthetic ingredients, and rigorous third-party testing.

The Bottom Line

Relief Factor is designed to help alleviate joint pain associated with exercise, aging, and everyday living. The formula is 100% drug-free and made with icariin, turmeric, resveratrol, and omega-3 to support your body’s natural healing process and help reduce pain and inflammation.

The company offers a three-week trial for just $19.99 (plus S&H). After that, your subscription automatically renews at a higher cost of $79.99 each month until canceled.

Relief Factor accepts returns within 90 days, but products must be shipped back unopened, and the company will not refund the cost of shipping and handling.

Natural, safe GRAS ingredient. Non-chemical, eco-friendly manufacturing process in an FDA regulated GMP facility. Made in the USA. 100% domestic. Contains no fillers, binders, or synthetic ingredients, and rigorous third-party testing.

The Bottom Line

This was one of the only products we could verify had no hidden additives or artificial ingredients. It was also one of the only collagen supplements third-party tested.

Their return policy was topnotch — a comprehensive 60-day, risk-free, money-back guarantee proving the company stands behind its products.

This was a huge advantage versus the competition, along with total effectiveness projections that rivaled any other supplement we found.

There are several product variations, but all Osteo Bi-Flex formulations contain glucosamine and “Joint Shield 5-Loxin Advanced,” which is the brand’s trademarked moniker for Boswellia serrata extract.

There are several product variations, but all Osteo Bi-Flex formulations contain glucosamine and “Joint Shield 5-Loxin Advanced,” which is the brand’s trademarked moniker for Boswellia serrata extract.

Osteo Bi-Flex Triple Strength contains several active ingredients that are well supported by research and could be beneficial when combined with other lifestyle factors.

The Bottom Line

Now Foods products are often hit or miss. Luckily this time the “UC-II, Undenatured Type II Collagen” product is well worth the price.

Cartilage is one of the primary connective tissues of the body, providing flexibility and support to bone joints. Undenatured Type II Collagen is the principal structural protein in cartilage that is responsible for its tensile strength and toughness.

Derived from chicken sternum cartilage, UC-II consists of Undenatured (native) Type II Collagen that works with the immune system to support healthy joints and promote joint mobility and flexibility.

UC-II’s patent protected composition has demonstrated its efficacy in human clinical studies. NOW UC-II is enhanced with Aquamin Red Algae Minerals, a natural source of calcium and over 70 trace minerals.

The Bottom Line

Neocell Joint Complex is sold at a mid-price range per bottle of 120 capsules. There are no discounts offered when purchasing larger amounts of the supplement, but the manufacturer does have a monthly subscription program which gives the customer 25% off per bottle.

Additionally, there is mention of return policy, but full details are not provided regarding terms and conditions and free samples are not available to try.

Neocell Joint Complex contains a blend of ingredients often used in joint health support supplements. The product label for the supplement is shown on the website but while all ingredients are listed, the source and quality used in the blend are not disclosed.

The formula contains several key ingredients that are thought to help build stronger joints including Hydrolyzed Chicken Collagen, Protein, and Sodium which are said to support cartilage in joints.

The Bottom Line

Support joint health and flexibility with Fast-Acting Joint Formula Capsules from Life Extension®. This dietary supplement could ease inflammation and fight oxidative stress.

Taking Life Extension Fast Acting Joint Formula is a good preventative measure to provide the body what it needs to synthesize collagen, an important protein for joint and ligament health

Hyal-Joint™‚ with hyaluronic acid‚ collagen and glycosaminoglycan complex‚ may lubricate joints and support easy movement.

Take Fast-Acting Joint Formula Capsules from Life Extension® everyday and it could improve joint function and restore its structure‚ while easing pain and inflammation.

The Bottom Line

Tribe’s vegan capsules contain 112.5mg per serving. The company also makes sure to produce their supplements in Good Manufacturing Practice (GMP) approved facilities.

This nutrient is best absorbed when combined with black pepper (or piperine), which this brand includes. Experts from the Arthritis Foundation suggest that 100 mg daily can help ease osteoarthritis pain.

This product contains collagen, boswellia, and turmeric—three joint health powerhouses.

It’s worth pointing out that it has been reported by customers that they did not experience any of the desired results and were disappointed with the product. Potential customers should also take into consideration that there is no money-back guarantee for Boswellia Complex Capsules.

The Bottom Line

This is an Omega-3 supplement that has been formulated to reduce and ultimately get rid of inflammation, joint pain, and muscle aches/soreness that often stem from aging and working out.

It consists of a mixture of Omega-3 fatty acids and some more natural ingredients that have been proven scientifically to help alleviate joint pains.

DHA and EPA are essential for their anti-inflammatory characteristics. Furthermore, they also lower the risks of developing chronic diseases [2]. DHA supports brain development and eye health.

Other major ingredients[3] in Omega XL include; Pema canaliculus Oil Extract, Olive oil, omega-3 fatty acids, and vitamin E

The Bottom Line

Joint Collagen Tablets Advanced Formula + Boswellia is Coming in at number 4 on our list.

Nicole M. Avena, Ph.D., a nutrition consultant and assistant professor of neuroscience at the Mount Sinai School of Medicine, likes youtheory’s variety because the company has been in the collagen supplement game for a long time.

However, this formula is still missing some key ingredients, such as eggshell membrane, UC-II Collagen, and others. They fell to number 10 on our list because they use generic ingredients and not the clinically studied versions.

Their ingredients are sourced from all over the world to ensure the highest quality, and their products are manufactured in their own facility,” says Avena. Youtheory’s facility is also GMP certified.